Intestinal Lipodystrophy (Whipple's Disease)

Whipples disease: a review

Whipple’s disease was described in 1907 and given the name “intestinal lipodystrophy” until it was found that the agent responsible is a bacterium named Tropheryma whipplei. It’s a rare disease which occurs predominantly in males aged 30-60. The small intestinal mucosa is always affected with lesions that are specific to this disease. Replacement of most of cellular elements in the lamina propr...

Peripheral neuropathy in Whipples disease: a case report.

Whipples disease is a chronic multisystem inflammatory disease with predominantly gastrointestinal manifestations due to Tropheryma whipplei infection. Typical neurological abnormalities include dementia, eye movement abnormalities, hypothalamic dysfunction and oculomasticatory myorhythmias. The literature on peripheral neuropathy in Whipples disease is sparse and the involvement of peripheral ...

Partial lipodystrophy in coeliac disease.

The association of coeliac disease and partial lipodystrophy is described. The patient also had deficiencies of serum IgA and C3 complement (the latter associated with partial lipodystrophy). In addition, there was subclinical dermatitis herpetiformis confirmed by skin biopsy. The facial wasting of fully developed partial lipodystrophy may be misinterpreted as a sign of malabsorption but the fa...

Generalized Lipodystrophy.

[Mesenteric lipodystrophy].

Mesenteric lipodystrophy is a rare disorder characterized by either focal or diffuse thickening of the mesentery due to chronic inflammation and fibrosis. The etiology and pathogenesis is obscure. Roentgenologic findings help in differential diagnosis with other diseases but they rarely establish the diagnosis. This is made in most cases by laparotomy.